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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHEK1
All Species:
0
Human Site:
S147
Identified Species:
0
UniProt:
O14757
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14757
NP_001107593.1
476
54420
S147
E
R
D
N
L
K
I
S
D
F
G
L
A
T
V
Chimpanzee
Pan troglodytes
XP_001145968
476
54387
Rhesus Macaque
Macaca mulatta
XP_001111357
476
54432
Dog
Lupus familis
XP_852191
460
52810
Cat
Felis silvestris
Mouse
Mus musculus
O35280
476
54363
Rat
Rattus norvegicus
Q91ZN7
476
54410
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513209
476
53924
Chicken
Gallus gallus
Q8AYC9
476
53830
Frog
Xenopus laevis
Q6DE87
474
53957
Zebra Danio
Brachydanio rerio
NP_956487
410
46756
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61661
512
57815
Honey Bee
Apis mellifera
XP_623436
467
53927
Nematode Worm
Caenorhab. elegans
Q9N3Z3
503
56917
Sea Urchin
Strong. purpuratus
NP_001091925
468
52554
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84VQ3
439
49610
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
93.2
N.A.
93.2
94.3
N.A.
89.9
84.4
77.7
56.9
N.A.
46
45.5
32
57.9
Protein Similarity:
100
100
99.7
95.1
N.A.
97
97.2
N.A.
95.3
91.5
86.7
71
N.A.
62.8
63.8
48.7
73.3
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
0
0
0
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
100
0
0
0
0
0
100
0
0
0
0
0
0
% D
% Glu:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
0
100
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _